Important: New USP PVT Test Standard, starting in May 2023
The USP has revised General Chapter <711> Dissolution, and one of the changes is the introduction of a new reference standard tablet known as the USP Dissolution Performance Verification Standard (DPVS).
Langen, March 27th, 2023
The DPVS is a new reference standard for Prednisone that offers improved reproducibility and sensitivity to operational and mechanical variables of instrument setup while being less sensitive to media degassing. It comes in blister packs of six tablets and is packaged in an aluminum sachet to provide additional protection against moisture.
Starting from May 1st, 2023, the DPVS will become the only valid standard for Performance Verification Testing (PVT). PVTs performed before this date using the current valid Prednisone lot will remain valid until their normal duration period ends. After May 1st, the USP will not require an additional PVT for units that have already undergone PVT using the old Prednisone standard for the normal duration period each company uses.
ERWEKA already has the new DPVS tablets in stock ready to ship. Our service team will of course use the new DPVS starting from May 1st, 2023.
For more Information, please have a look at the official USP FAQ regarding the new DPVS: https://www.uspnf.com/notices-711-nitr-faq